Nancy Guthrie Latest: Genealogy Testing Underway after FBI Confirms No CODIS Hit on DNA

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An FBI official says investigative genetic genealogy is underway in the Nancy Guthrie investigation. This after DNA found on a glove matching the type worn by the subject seen in surveillance video outside Guthrie’s home the morning she disappeared resulted in no CODIS hits. DNA recovered inside the home also yielded no matches.

FAST FACTS

  1. The search for Nancy Guthrie entered its third week on Sunday. The 84-year-old disappeared from her home in Tucson, Arizona, 17 days ago.
  2. Pima County Sheriff Chris Nanos cleared Nancy Guthrie’s family as suspects in her disappearance case, calling them “victims” who have been cooperative.
  3. Authorities still have no suspects or persons of interest, though Pima County Sheriff Chris Nanos said more law enforcement operations are expected in the coming days.
  4. A glove with a DNA profile of an unknown male has been recovered, and appears to match the pair worn by a subject seen in surveillance video outside Nancy Guthrie’s home, the FBI said Sunday. Investigative genetic genealogy is underway after the DNA resulted in no CODIS hits.
  5. The FBI released a description of the suspect seen in a mask and gloves tampering with the doorbell camera in front of Nancy Guthrie’s home in the early morning hours of Feb. 1 around the time she went missing. The suspect is described as a male between 5’9” – 5’10” tall, with an average build and was seen carrying a 25-liter “Ozark Trail Hiker Pack” backpack.
  6. The FBI increased its reward to $100,000 for information leading to the location of Nancy Guthrie or the arrest and conviction of anyone involved in her disappearance.

Sheriff says case far from being cold, as investigators pursue thousands of leads

Sheriff says case far from being cold, as investigators pursue thousands of leads

Ty ONeil/AP Photo

Pima County Sheriff Chris Nanos said the Nancy Guthrie case is far from being cold, stressing that it will not be considered cold as long as there are leads to pursue.

The sheriff said 400 investigators continue to work on thousands of tips and leads, according to NBC News.

“As long as we have the ability to chase a lead, it’s not cold,” Nanos said on Tuesday, according to the outlet.

‘We’re not going to give up. We’re going to find Nancy, and we’re going to find out who did this,” he added.

Posted by Landon Mion

4 hours ago

Archbishop of New York leads prayer on ‘Today’ show seeking Nancy Guthrie’s safe return

Archbishop of New York leads prayer on 'Today' show seeking Nancy Guthrie's safe return

Nathan Congleton/NBC via Getty Images

The archbishop of New York on Tuesday led a prayer on NBC’s “Today” show calling for the safe return of Nancy Guthrie, the 84-year-old mother of the show’s co-host, Savannah Guthrie.

Archbishop Ronald Hicks was selected by Pope Leo XIV in December to take over the position, and he assumed the role earlier this month.

Hicks was asked by NBC host Hoda Kotb about any words he wished to share with the Guthrie family, as authorities continue to search for the missing woman.

“It’s heartbreaking,” he said. “It’s hard to watch.”

“I want to just extend my absolute support, and especially my prayers, not only my own prayers, but she has a community of people who are praying for her and for her mom and for the entire family,” Hicks continued.

Sheriff says photo may show Nancy Guthrie suspect wearing ring

Sheriff says photo may show Nancy Guthrie suspect wearing ring

The FBI released new surveillance footage of the suspect in the disappearance of Nancy Guthrie on Feb. 1, 2026. (X/ @FBI DirectorPatel)

Pima County Sheriff Chris Nanos told NBC that he has seen a photo that could show the suspect in the Nancy Guthrie case wearing a ring, but said investigators will analyze the image before drawing any conclusions.

“I look at the same photo you look at and I get, I see it,” Nanos said.

He added that the image would be reviewed more closely by investigators.

“I’m going to give that to my team,” he said. “They’ll look at that. They’ll analyze it and we’ll see. Maybe, maybe it is.”

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Sheriff still awaiting video from Nancy Guthrie’s cameras

Sheriff still awaiting video from Nancy Guthrie’s cameras

Aerial drone shots of missing person Nancy Guthrie’s home on Tuesday, Feb. 3, 2026 in Tucson, Arizona. (Fox Flight Team)

Investigators have not yet obtained video from additional cameras at Nancy Guthrie’s home.

Pima County Sheriff Chris Nanos told NewsNation correspondent Brian Entin that authorities still do not have video from Guthrie’s other cameras and that the video is currently “in the hands of Google.”

It was not immediately clear what type of cameras were involved or how long it may take for investigators to retrieve the material. 

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Genetic genealogy that caught notorious killers now used in Nancy Guthrie case

Genetic genealogy that caught notorious killers now used in Nancy Guthrie case

Savannah Guthrie and her mother, Nancy Guthrie, are pictured together in 2023. (Nathan Congleton/NBC via Getty Images)

Investigators looking to track down Nancy Guthrie’s suspected kidnappers are turning to a relatively new technology that has been attributed to solving some of the most prolific criminal and cold cases in American history.

Investigative genetic genealogy (IGG) is defined as “the science of using genetic and genealogical methods to generate leads for law enforcement entities investigating crimes and identifying human remains,” according to the International Society of Genetic Genealogy.

Investigators use a DNA sample to search for genetic familial matches, ultimately looking to narrow down potential identities by zeroing in on close relatives of the individual.

On Tuesday, the FBI confirmed to Fox News Digital that IGG was being used to test DNA found on a glove discovered two miles from Nancy Guthrie’s home and other DNA samples found inside her house.

Find out more about how IGG could help solve the case.

This is an excerpt from a story by Fox News Digital’s Julia Bonavita.

Sheriff dispels Adult Protective Services speculation in Nancy Guthrie case

Sheriff dispels Adult Protective Services speculation in Nancy Guthrie case

Pima County Sheriff Chris Nanos (Jan Sonnenmair/Getty Images)

Pima County Sheriff Chris Nanos addressed speculation involving Adult Protective Services in the case of missing 84-year-old Nancy Guthrie, clarifying that after a neighbor made a call, APS sent an investigator to her home the day she was reported missing.

“The day she was reported missing a neighbor called Adult Protective Services,” Nanos said. “They sent an investigator to check on her.”

Fox News Digital’s Michael Ruiz contributed to this report.

Border Patrol’s BORSTAR team used blue shirt in Guthrie K-9 search

Border Patrol’s BORSTAR team used blue shirt in Guthrie K-9 search

A bright blue shirt located along the walkway to Nancy Guthrie’s home, in Tucson, Arizona, Tuesday, Feb. 3, 2026. (Derek Shook for Fox News Digital)

U.S. Border Patrol confirmed to Fox News its elite BORSTAR search and rescue team used the bright blue shirt seen lying along the walkway at Nancy Guthrie’s home as part of a K-9 scent search at the property.

Border Patrol says the BORSTAR team, along with a K-9, was called to Guthrie’s home twice — first on the night she went missing and later when the FBI returned to the residence. During those deployments, the team conducted a search using the scent from the blue shirt.

Fox News Digital previously reported that Pima County Sheriff Chris Nanos said the bright blue shirt was used by a U.S. Border Patrol K-9 team and had been left behind and later retrieved. The shirt was visible on video recorded by Fox News Digital on Feb. 3, two days into the search.

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The garment was seen lying near blood drops on Guthrie’s front steps.

Sheriff outlines next DNA testing steps in Nancy Guthrie case

Sheriff outlines next DNA testing steps in Nancy Guthrie case

FBI agents canvass homes near Nancy Guthrie’s home in Tucson, Friday, Feb. 6, 2026. (Kat Ramirez for Fox News Digital)

Pima County Sheriff Chris Nanos said investigators are now debriefing recent forensic findings and prioritizing additional lab work as the investigation into the disappearance of 84-year-old Nancy Guthrie continues.

Nanos told Fox News Digital that the next phase will include separating merged DNA samples recovered inside Guthrie’s residence, conducting further testing and evaluating whether any viable material could be used for investigative genetic genealogy or entered into CODIS.

Nanos said each step requires laboratory analysis before investigators can move forward.

2 men with badges seen entering home next to Nancy Guthrie’s residence

FBI official confirms investigative genetic genealogy being used in Nancy Guthrie case

FBI official confirms investigative genetic genealogy being used in Nancy Guthrie case

Photos released on Feb. 10, 2025, show a “subject” on Nancy Guthrie’s property. (Provided by FBI)

An FBI official tells Fox News Digital that investigative genetic genealogy (IGG) is already underway in the Nancy Guthrie investigation.

IGG is a forensic method that uses crime scene DNA to identify potential relatives through public genealogy databases when traditional law enforcement databases like CODIS produce no matches.

Earlier Tuesday, the FBI and Pima County Sheriff’s Department said the unknown male DNA profile on a glove found two miles from Nancy Guthrie’s home did not result in any CODIS hits. The DNA found in her home also produced no hits, according to the sheriff’s department.

“The DNA found at the property is being analyzed & further testing needs to be done as part of the investigation,” the sheriff’s department said on X.

CeCe Moore, the chief genetic genealogist at Parabon NanoLabs, told Fox News Digital she has full confidence that investigative genetic genealogy will be able to identify that DNA contributor.

“Thanks to the power of investigative genetic genealogy, it is just a matter of time now until they discover who that DNA belongs to and the investigators are able to pursue those leads and, hopefully, provide answers to Nancy’s family,” she said.

Advanced signal-detection technology used in Nancy Guthrie search

Advanced signal-detection technology used in Nancy Guthrie search

Members of the press work outside the home of Nancy Guthrie, the missing mother of “Today” show host Savannah Guthrie, Thursday, Feb. 5, 2026, in Tucson, Ariz. (AP Photo/Caitlin O’Hara)

Authorities deployed specialized Bluetooth and Wi-Fi detection technology during the search for Nancy Guthrie, according to a statement from Parsons Corporation, which said it began assisting the Pima County Sheriff’s Department earlier this month.

“At the beginning of February, the Pima County Sheriff’s Department requested our support, and we immediately began deployment of BlueFly® units and personnel to Arizona to assist with the search for Nancy Guthrie,” the company said.

Parsons described BlueFly® as “a Bluetooth and Wi-Fi sensor intended for search and rescue operations in challenging environments,” adding that the technology “has been used on a variety of air and ground vehicles, and on foot in austere terrain.” The system “provides first responders with a heat map to identify signals within a search area.”

According to the statement, BlueFly® was used Feb. 3 during the sheriff department’s search and rescue helicopter operation over the Guthrie neighborhood and was later deployed in additional search efforts by helicopter, ground vehicles and on foot.

“Due to the sensitivity of the investigation, we will not provide additional details on ongoing operations,” the company said.

Sheriff says no evidence Nancy Guthrie taken to Mexico

Sheriff says no evidence Nancy Guthrie taken to Mexico

A member of the Pima County sheriffs office remains outside of Nancy Guthrie’s home, Monday, Feb. 9, 2026 in Tucson, Ariz. (AP Photo/Ty ONeil; Nathan Congleton/NBC via Getty Images)

Pima County Sheriff Chris Nanos said there is no evidence Nancy Guthrie was taken across the border into Mexico, though investigators are aware of the region’s proximity as the search for the 84-year-old continues.

During an interview with Fox News’ Jonathan Hunt, Nanos was asked whether authorities were considering the possibility that Guthrie may have been transported into Mexico.

“You know, I’m sure the FBI has looked into that as well, but no,” Nanos said. “We check all the leads we have…we’re like everybody else. We know where Mexico is in relationship to this, and it’s a possibility. But no, we have nothing to indicate that.”

Nanos emphasized that investigators are continuing to follow available leads but have not uncovered any information suggesting Guthrie was taken across the border. The investigation remains ongoing.

2 men arrive at Nancy Guthrie’s home Tuesday afternoon

Two men were seen walking the grounds of 84-year-old Nancy Guthrie’s property Tuesday as the search continues for the missing woman.

Drone footage captured by Fox’s Flight Team shows the pair moving around the residence and into the backyard before entering the garage through an exterior-facing door.

It was not immediately clear who the two men were or whether they were law enforcement officials connected to the investigation, which remains ongoing. Authorities have released few details about the latest steps in the case.

Sheriff disputes reports as gun store owner describes FBI visit

An Arizona gun store owner says an FBI agent showed him pages of photos and names tied to a kidnapping probe and asked him to check for recent gun purchases – even as Pima County Sheriff Chris Nanos disputes reports investigators have narrowed their focus to specific people.

Phillip Martin, co-owner of Armor Bearer Arms in Tucson, told Fox News an FBI agent visited his store with three pages containing photos and the names of roughly 18 to 24 people, asking whether any had purchased a firearm there within the past year.

“He actually had given me a list of paper, list of people that had pictures and names on it, and he wanted to know if I could help him pull up in my system if any of these people have purchased a gun in the last year,” Martin said.

Martin said he was initially skeptical but agreed to help out of sympathy for the victim’s family.

“Anything that could help them find the person I was willing to help,” he said.

According to Martin, he typed each last name into the store’s system, which would display identifying information if the person had made a purchase. He said none of the names returned a match.

The agent, Martin said, told him investigators planned to visit other gun shops to check whether anyone on the list had bought a firearm in the past year.

During an interview with Fox News’ Jonathan Hunt, Pima County Sheriff Chris Nanos pushed back on reports that investigators were asking gun stores about around 40 people.

“That’s not true,” Nanos said when asked whether authorities had narrowed the suspect pool to a few dozen individuals.

Nanos said investigators have not zeroed in on a specific group but are instead working through evidence that includes DNA, Ring camera footage and potential leads tied to a Walmart.

“We haven’t narrowed it down to anything other than we have pieces of evidence that we’re looking at to try to find this individual,” Nanos said.

Posted by Greg Wehner

Breaking News15 hours ago

DNA testing in Nancy Guthrie case yields no database match

The unknown male DNA profile on a glove found two miles from the home of Nancy Guthrie has been run through the FBI’s DNA database – and did not result in any hits, Pima County Sheriff Chris Nanos told Fox News chief correspondent Jonathan Hunt in an interview on Tuesday.

DNA recovered from Guthrie’s home also did not match records in the FBI database, Nanos said. The sheriff confirmed that the DNA on the glove was different from the DNA found inside the home.

The FBI confirmed the news to Fox News Digital on Tuesday.

“We’re hopeful that we’re always getting closer, but the news now, I think, is we had heard this morning that, of course, the DNA on the glove that was found two miles away was submitted for CODIS. And I just heard that, CODIS had no hits,” Nanos said.

The sheriff’s department later provided clarity, writing on X: “The DNA that was submitted to CODIS was from the set of gloves found 2 miles away.

“It did not trigger a match in CODIS & did not match DNA found at the property,” it said. “The DNA found at the property is being analyzed & further testing needs to be done as part of the investigation.”

Pima County sheriff gives update on blue shirt left outside Nancy Guthrie’s home

Pima County sheriff gives update on blue shirt left outside Nancy Guthrie’s home

A bright blue shirt seen along the walkway leading up to the home of Nancy Guthrie in Tucson, Arizona, on Feb. 3, 2026. (Derek Shook for Fox News Digital)

Pima County Sheriff Chris Nanos told Fox News on Tuesday that a blue shirt seen lying along the walkway leading up to Nancy Guthrie’s home had been left by federal law enforcement.

Nanos said the bright blue shirt was used by a U.S. Border Patrol K-9 team. The shirt was left behind and then retrieved.

The shirt was seen on video recorded by Fox News Digital on Feb. 3, two days into the search for Nancy Guthrie. The shirt was not far from a trail of blood drops on Nancy Guthrie’s front steps.

Milwaukee attorney offers $100K reward for info leading to arrest in Guthrie case

Milwaukee attorney offers $100K reward for info leading to arrest in Guthrie case

A member of the Pima County sheriffs office remains outside of Nancy Guthrie’s home, Monday, Feb. 9, 2026 in Tucson, Ariz. (Ty ONeil/AP Photo)

A Milwaukee attorney told FOX6 Milwaukee that he is offering a new $100,000 reward in the Nancy Guthrie case.

Michael Hupy, who is also the president of Milwaukee Crime Stoppers, said he is offering the reward locally through Crime Stoppers for any information that leads to an arrest.

“She’s an 84-year-old woman and I don’t like the way the investigation and reward is being handled. I think it could have been done much better,” Hupy told the station. “I think if the $100,000 was put up through crime stoppers – we could be further along.”

Hupy said he believes that even though the FBI has its own $100,000 reward, its requirement for personal information may discourage tips from the public. Crime Stoppers allows tipsters to remain anonymous.

“This woman has been missing for two or three weeks and no leads have amounted to anything,” he told the station. “So if the person who knows who the perpetrator is doesn’t want his name exposed, wants a reward and has information that will lead to an arrest – crime stoppers is the perfect place to do it.”

He said the reward will be posted through Crime Stoppers of Tucson.

“No one did it, so I am doing it,” Hupy said of his reward offer.

Vehicle towed from home FBI raided Friday at direction of insurance company, not law enforcement

A vehicle parked outside a home in Catalina Foothills that was raided by the FBI on Friday was towed away by an insurance company — not law enforcement — on Monday.

A neighbor told Fox News Digital that the vehicle, which appeared to have significant front end damage, was towed at the request of State Farm after it was totaled in a crash last week.

The neighbor added that the car’s owner is “pissed” about the Friday night raid, and his mother is upset because she doesn’t know what’s going on — but everyone wants Nancy Guthrie found.

Posted by Peter D’Abrosca

20 hours ago

Former Laci Peterson detective on how investigators clear family members in missing persons cases

A retired detective told “FOX & Friends” how investigators in Nancy Guthrie’s disappearance may have examined her family members before clearing them in the case.

Jon Buehler, who worked as an investigator on the Laci Peterson missing persons case in California over two decades ago, detailed the process that law enforcement usually goes through when trying to pin down a suspect in such a case.

“Generally, what you’re going to do is you’re going to take a look at where family members were when the abduction took place and verify their alibi that they weren’t involved in it,” Buehler said. “You’re going to take a look at their friends and associates and make sure that none of them have a criminal record or past history of violence or anything like that, maybe gambling debts or things like that, that would put them in a position to target Nancy.”

Buehler noted that the process requires “a lot of legwork” by detectives that would keep them busy.

“But if the sheriff said that he’s confident that they’re not part of it, then we have to go with that,” Buehler said, referring to Pima County Sheriff Chris Nanos announcing that investigators cleared the Guthrie family — including siblings and spouses — in the case.

The sheriff’s announcement came as the FBI was awaiting forensic testing results on a glove that had a DNA profile of an unknown male. The recovered glove appears to match the gloves of the subject seen in the surveillance video, the FBI has said.

Buehler said that a timeline on getting results in a case like this will likely be expedited to the “front of the line” due to the intensity of the media coverage and public interest.

He added, however, that the timeline on getting the results is “not like plugging in a wall socket or anything like that,” and may take time.

“It takes those criminalists in the lab time to find the results and quantify them, get them written down, and then have ready to go to the next step, whoever’s going to look at it, whether it’s Quantico or an intermediary, that’s going to determine the quality is still there for further examination,” the retired detective said.

Guthrie’s family cleared as suspects in ‘first few days,’ sheriff says

Guthrie’s family cleared as suspects in ‘first few days,’ sheriff says

Pima County Sheriff Chris Nanos gives an update on the investigation after the disappearance of Nancy Guthrie, the 84-year-old mother of U.S. journalist and television host Savannah Guthrie, who went missing from her in Tucson, Arizona, February 5, 2026. (Rebecca Noble/Reuters)

Pima County Sheriff Chris Nanos told local Tucson station KOLD13 that Nancy Guthrie’s family members were ruled out as suspects “in the first few days” of the investigation.

Nanos on Monday issued a public message clearing the Guthrie family out of concern they were being unfairly targeted amid the investigation into the 84-year-old’s disappearance.

Nanos described the Guthrie family as “nothing but cooperative and gracious” and emphasized that they are victims in the case.

NBC News national law enforcement and intelligence correspondent Tom Winter said the sheriff likely felt so strongly about making such a statement because there has been a lot of incorrect online speculation surrounding the case.

“Throughout the entirety of this investigation, there’s not a single person that I have talked to that’s been briefed on it, is familiar with all the facts of the case, that has ever said there was a single piece of evidence that tied back to any member of the Guthrie family, period,” Winter said on NBC’s “Today.”

Nancy Guthrie’s pacemaker remains best hope of finding missing 84-year-old, expert says

While detecting the signal of Nancy Guthrie’s pacemaker may be like searching for a needle in a haystack, an expert says it remains the best hope of finding the missing 84-year-old, Griff Jenkins, co-host of “FOX & Friends Weekend,” reported from Tucson, Arizona, on Tuesday morning.

Jenkins reported that Dave Kennedy, who created the new Bluetooth “signal sniffing” technology, told him that the type of pacemaker Nancy Guthrie has is “the best we could hope for.”

“It essentially every one to three minutes sends a simple ping up that says, ‘Hey, iPhone. Are you there?’ Well, in this case, if the ‘signal sniffer’ in the sky can pick it up, it can locate it, do a triangulation of directional antennas and within an hour they could possibly find her,” Jenkins reported.

Jenkins also flew in a helicopter over the search area’s challenging terrain of rough hills and steep culverts, providing a birds-eye view similar to what law enforcement has seen while using the new high-tech Bluetooth scanner in the search for Nancy Guthrie.

“It’s much like hunting for a needle in a haystack,” Jenkins said.

Glove DNA in Nancy Guthrie case expected to be entered into CODIS soon

An FBI official told Fox News Digital DNA recovered from a glove believed tied to the suspect in the Nancy Guthrie case is still undergoing quality control testing at the sheriff’s private lab in Florida after being sent from Tucson on Feb. 12.

Once that process is complete, the profile is expected to be entered into the FBI’s Combined DNA Index System, or CODIS, in the near future – possibly as soon as tonight – which could determine whether it matches anyone in the national database.

When asked whether more than one suspect could be involved, the official pointed to FBI Director Kash Patel’s comments on “Hannity” last week referencing “persons of interest,” indicating investigators are not ruling out the possibility of multiple individuals.

Credit: www.foxnews.com

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